The 18th Annual WORLDSymposium

Planning for WORLDSymposium 2022 is officially underway, and everyone is excited to meet again face-to-face in San Diego, February 7-11, 2022. In anticipation of continued global progress in managing the pandemic, initial plans are in place for a LIVE in-person gathering in San Diego at the Manchester Grand Hyatt Hotel. In addition, plans are underway to include an alternative VIRTUAL format to supplement the live meeting, and allow for registration for those who are unable to attend in person. This format will include ways to connect with other attendees, both live and virtual, and interact with our sponsors.

Registration for the conference opens: August 1, 2021
Advance Registration Deadline: January 7, 2022

We are passionate about raising the quality and enhancing the research presentations at WORLDSymposium 2022, broadening our reach, and keeping you connected during a time when flexibility is so crucial.

The WORLDSymposium Annual Meeting is the largest lysosomal disease meeting and exposition in the world. This year’s meeting is expected to attract over 3,000 scientific attendees from more than 60 different countries, plus almost 40 exhibiting companies. The meeting provides a forum for the presentation and discussion of cutting-edge science in all areas of lysosomal disease research and lysosomal storage disease research.


WORLDSymposium™ is an annual research conference dedicated to lysosomal diseases. WORLD is an acronym that stands for We’re Organizing Research on Lysosomal Diseases.

WORLDSymposium is designed for basic, translational and clinical researchers, patient advocacy groups, clinicians, and all others who are interested in learning more about the latest discoveries and the clinical investigation of lysosomal diseases.

Learning Objectives

At the completion of this program, the participant should be able to:

  • Identify the key diagnostic features of lysosomal diseases.
  • Utilize recent diagnostic tests for lysosomal diseases.
  • Compare the relative advantages and disadvantages of each therapy currently available.
  • Identify unmet needs of each disease being discussed.
  • Formulate new research ideas for these lysosomal diseases.
  • Describe the impact on, and changes to, lysosomal and rare disease research due to the COVID-19 pandemic. 

About WORLDSymposium

WORLDSymposium is a multidisciplinary forum presenting the latest information from basic science, translational research, and clinical trials for lysosomal diseases. Originally conceived in 2004 in response to an NIH RFP for rare diseases, WORLDSymposium is often cited as the most important scientific meeting on lysosomal molecular biology, disorders and treatment.

WORLDSymposium has become the major educational and unifying activity of lysosomal disease researchers, and has evolved into a highly interactive research activity. The underlying theme “transitioning molecular biology to human therapies” seeks to elucidate the challenges—and highlight the successes—in bringing bench discoveries into successful clinical therapies.

The main emphasis of the meeting remains the same: to assess the mechanisms, and obstacles, for taking bench research into human therapy.