The 18th Annual WORLDSymposium

WORLDSymposium will be conducting the 2022 Annual Research Conference as a hybrid event. The live component will be held at the Manchester Grand Hyatt in San Diego, California, USA and a “virtual” platform will be available for remote attendees and will include many of the core elements of the in-person Annual Research Conference. This hybrid format will include new ways to connect with other attendees, announce new research and trials, interact with our sponsors.

Registration for the conference opens: August 1, 2021
Advance Registration Deadline: January 7, 2022

As we develop this hybrid experience, we are passionate about raising the quality and enhancing the research presentations at WORLDSymposium 2022, broadening our reach, and keeping you connected during a time when flexibility is so crucial. Use this form to share your thoughts and ideas on how we can make the WORLDSymposium 2022 Annual Research Conference more valuable to our attendees and sponsors.

The WORLDSymposium Annual Meeting is the largest lysosomal disease meeting and exposition in the world. This year’s meeting is expected to attract over 3,000 scientific attendees from more than 60 different countries, plus almost 40 exhibiting companies. The meeting provides a forum for the presentation and discussion of cutting-edge science in all areas of lysosomal disease research and lysosomal storage disease research.


WORLDSymposium™ is an annual research conference dedicated to lysosomal diseases. WORLD is an acronym that stands for We’re Organizing Research on Lysosomal Diseases.

WORLDSymposium is designed for basic, translational and clinical researchers, patient advocacy groups, clinicians, and all others who are interested in learning more about the latest discoveries and the clinical investigation of lysosomal diseases.

Learning Objectives

At the completion of this program, the participant should be able to:

  • Identify the key diagnostic features of lysosomal diseases.
  • Utilize recent diagnostic tests for lysosomal diseases.
  • Compare the relative advantages and disadvantages of each therapy currently available.
  • Identify unmet needs of each disease being discussed.
  • Formulate new research ideas for these lysosomal diseases.
  • Describe the impact on, and changes to, lysosomal and rare disease research due to the COVID-19 pandemic. 

About WORLDSymposium

WORLDSymposium is a multidisciplinary forum presenting the latest information from basic science, translational research, and clinical trials for lysosomal diseases. Originally conceived in 2004 in response to an NIH RFP for rare diseases, WORLDSymposium is often cited as the most important scientific meeting on lysosomal molecular biology, disorders and treatment.

WORLDSymposium has become the major educational and unifying activity of lysosomal disease researchers, and has evolved into a highly interactive research activity. The underlying theme “transitioning molecular biology to human therapies” seeks to elucidate the challenges—and highlight the successes—in bringing bench discoveries into successful clinical therapies.

The main emphasis of the meeting remains the same: to assess the mechanisms, and obstacles, for taking bench research into human therapy.