Robert J. Gorlin Symposium

Precision Metrics for Cognition

Program Chair: Elsa Shapiro, PhD
February 6, 2022
3:00 – 5:00 PM Pacific Standard Time (PST)

WORLDSymposium is excited to announce a new annual session: The Robert J. Gorlin Symposium. This new course will honor the work of Robert James Gorlin, DDS, PhD. Dr. Gorlin was an maxillofacial pathologist, geneticist and academician at the University of Minnesota School of Dentistry. His groundbreaking research in genetic disorders of the head and neck, spanning over 50 years, revolutionized the understanding of the morphology of lysosomal diseases and many other genetic disorders. The inaugural Robert J. Gorlin Symposium, Precision Metrics of Cognitive Change, will take place Sunday, February 6, 2022 from 3:00 – 5:00 PM Pacific Standard Time (PST). Plan ahead to ensure you arrive in time to attend this groundbreaking session.

This new session at WORLDSymposium 2022 is intended to discuss the urgent need to develop and implement precise metrics for measuring cognitive change in children with lysosomal diseases. Precision Metrics for Cognition will bring together leading experts to provide an explanation and rationale for using growth scale values (GSVs) to measure developmental longitudinal cognitive change in children with early onset and severe lysosomal diseases.

Through examples and case studies, experts will share more about the need for increased precision in measuring cognitive change and how GSVs are useful when facing the challenge of revealing the developmental trajectory of young children.

The goal of this session is provide attendees with insight into the perspective of regulatory bodies, and determine how to apply this approach in their research to reliably and precisely measure cognitive change.

Target audience

Research scientists, psychologists, physicians and health care industry actively involved in researching and developing treatments for patients with lysosomal diseases.

Preliminary Agenda

3:00 PM Background and challenges in measuring cognitive outcome
3:15 PM Use of growth scale values (GSVs)  to measure cognition
3:30 PM Measuring cognitive outcomes in MPS I
3:45 PM Use of GSVs in natural history of MPS IIIB
4:00 PM Measuring change in the clinical arena
4:15 PM Future challenges in measuring cognitive growth
4:30 PM FDA perspectives on measuring cognitive outcomes
4:45 PM Panel Discussion
5:00 PM Adjourn

Registration Required.